Our lab has focused on unveiling new mitochondrial biology to help people who are suffered from metabolic diseases and to make people free from age-related diseases.
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Lee SI, Seo Y, et al. "HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320." Biochem Biophys Res Commun. 2023 Nov 25;691:149320.
Sophors Phorl, et al. "Opposing roles of HDAC6 in liver regeneration and hepatocarcinogenesis." Cancer Science. 2022;113:2311–2322.
Noh S, et al. "p32/C1QBP regulates OMA1-dependent proteolytic processing of OPA1 to maintain mitochondrial connectivity related to mitochondrial dysfunction and apoptosis." Sci Rep. 2020 Jun 30;10(1):10618.
Kim JY, et al. "Cortactin deacetylation by HDAC6 and SIRT2 regulates neuronal migration and dendrite morphogenesis during cerebral cortex development." Mol Brain. 2020 Jul 25;13(1):105.