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Publications

 

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  1. Lee SI, Seo Y, Oanh HT, Vo TTH, Go H, Kim MH, Lee JY. HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320. Biochem Biophys Res Commun. 2023 Nov 25;691:149320. doi: 10.1016/j.bbrc.2023.149320.

  2. Sophors Phorl, Azra Memon, Yuri Seo, Thi Oanh Hoang, Trung Nghia Tran, Le Minh Tri Nguyen, Chang Hoon Lee, Woon Kyu Lee, Joo-Yong Lee. Opposing roles of HDAC6 in liver regeneration and hepatocarcinogenesis. Cancer Science. 2022;113:2311–2322. doi: 10.1111/cas.15391.

  3. Noh S, Phorl S, Naskar R, Oeum K, Seo Y, Kim E, Kweon HS, Lee JY. p32/C1QBP regulates OMA1-dependent proteolytic processing of OPA1 to maintain mitochondrial connectivity related to mitochondrial dysfunction and apoptosis. Sci Rep. 2020 Jun 30;10(1):10618. doi: 10.1038/s41598-020-67457-w.

  4. Kim JY, Hwang HG, Lee JY, Kim M, Kim JY., 2020. Cortactin deacetylation by HDAC6 and SIRT2 regulates neuronal migration and dendrite morphogenesis during cerebral cortex development. Mol Brain. 2020 Jul 25;13(1):105. doi: 10.1186/s13041-020-00644-y.

  5. Han, S.H., Korm, S., Han, Y.G., Choi, S.Y., Kim, S.H., Chung, H.J., Park, K., Kim, J.Y., Myung, K*., Lee, J.Y*. and Kim, H*., 2019. GCA links TRAF6-ULK1-dependent autophagy activation in resistant chronic myeloid leukemia. Autophagy, pp.1-15. (*: co-corresponding authors)

  6. Jung, S., Han, M., Korm, S., Lee, S.I., Noh, S., Phorl, S., Naskar, R., Lee, K.S., Kim, G.H., Choi, Y.J. and Lee, J.Y., 2018. HDAC6 regulates thermogenesis of brown adipocytes through activating PKA to induce UCP1 expression. Biochemical and biophysical research communications.

  7. Park, S. Y., Phorl, S., Jung, S., Sovannarith, K., Lee, S. I., Noh, S., ... & *Lee, J. Y. (2017). HDAC6 deficiency induces apoptosis in mesenchymal stem cells through p53 K120 acetylation. Biochemical and biophysical research communications, 494(1), 51-56.  (*: co-corresponding authors)

  8. Chung, Hee Jin, Sovannarith Korm, Se-in Lee, Sophors Phorl, Solhee Noh, Miae Han, Rema Naskar, *Hongtae Kim, and *Joo-Yong Lee. "RAP80 binds p32 to preserve the functional integrity of mitochondria." Biochemical and Biophysical Research Communications (2017). (*: co-corresponding authors)

  9. Choi SJ, Lee HC, Kim JH, Park SY, Kim TH, Lee WK, Jang DJ, Yoon JE, Choi YI, Kim S, Ma J, Kim CJ, Yao TP, Jung JU, Lee JY*, Lee JS*. 2016 HDAC6 regulates cellular viral RNA sensing by deacetylation of RIG-I. EMBO J. 35(4):429-42 (*: Co-corresponding authors)

  10. Park SY, Korm S, Chung HJ, Choi S, Jang JJ, Cho S, Lim YT, Kim H*, Lee JY* 2016 RAP80 regulates epithelial mesenchymal transition related with metastasis and malignancy of cancer. Cancer Sci. 107(3):267-73 (*: Co-corresponding authors)

  11. Lee JY*, Kawaguchi Y, Li M, Kapur M, Cjoi SJ, Kim HK, Park SY, Zhu H, Yao TP*. 2015 Uncoupling of Protein Aggregation and Neurodegeneration in a Mouse Amyotrophic Lateral Sclerosis Model. Neurodegener Dis 15(6):339-49 (*: Co-corresponding authors)

  12. Kim HJ, Nagano Y, Choi SJ, Park SY, Kim H, Yao TP*, Lee JY*. 2015 HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation. Biochem Biophys Res Commun. 464(4):1235-40. (*: Co-corresponding authors)

  13. Ho Kim J, Franck J, Kang T, Heinsen H, Ravid R, Ferrer I, Hee Cheon M, Lee JY, Shin Yoo J, Steinbusch HW, Salzet M, Fournier I, Mok Park Y. 2015 Proteome-wide characterization of signalling interactions in the hippocampal CA4/DG subfield of patients with Alzheimer's disease. Sci Rep. 5:11138.

  14. Kim NC, Tresse E, Kolaitis RM, Molliex A, Thomas RE, Alami NH, Wang B, Joshi A, Smith RB, Ritson GP, Winborn, BJ, oore  J, Lee JY, Yao TP, Pallanck L, Kundu M, Taylor JP. 2013. VCP Is Essential for Mitochondrial Quality Controby PINK1/Parkin and this Function Is Impaired by VCP Mutations. Neuron 78(1): 65-80

  15. Lee JY, Nagano Y, Taylor JP, Lim KL, Yao TP. 2010. Parkin controls mitophagy by promoting impaired mitochondria ubiquitination and aggresome-like mitochondrial aggregate formation. J Cell Biol. 189(4):671-9. (Highlighted “In This Issue” section in J Cell Biol. 189 (4): 614.)

  16. Lee JY, Koga H, Kawaguchi Y, Tang W, Wong E, Gao YS, Pandey UB, Kaushik S, Tresse E, Lu J, Taylor JP, CuervoAM, Yao TP. 2010. HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy. EMBO J. 29(5):969-80 (Highlighted in Editor’s Choice in Science 2010. 327(5966):625).

  17. Lee JY, Yao TP. 2010. Quality control autophagy: A joint effort of ubiquitin, protein deacetylase and actin cytoskeleton. Autophagy. 6(4) 555-557.

  18. Norris KL, Lee JY, Yao TP. 2009. Acetylation goes global: the emergence of acetylation biology. Sci Signal. 2(97):pe76.

  19. Yun YP, Lee JY, Ahn EK, Lee KH, Yoon HK, Lim Y. Diesel exhaust particles induce apoptosis via p53 and Mdm2 in J774A.1 macrophage  cell line. 2009. Diesel exhaust particles induce apoptosis via p53 and Mdm2 in J774A.1macrophage cell line. Toxicol In Vitro. 23(1):21-8

  20. Jee BK, Lee JY, Lim Y, Lee KH, Jo YH. 2007. Effect of KAI1/CD82 on the beta1 integrin maturation in highly migratory carcinoma cells. Biochem Biophys Res Commun. 359(3): 703-8

  21. Gao YS, Hubbert CC, Lu J, Lee YS, Lee JY, Yao TP. 2007. Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis. Mol Cell Biol. 27(24): 8637-47

  22. Lee JY, Moon HJ, Lee WK, Chun HJ, Han CW, Jeon YW, Lim Y, Kim YH, Yao TP, Lee KH, Jun TY, Rha HK, Kang JK.2006. Merlin facilitates ubiquitination and degradation of transactivation-responsive RNA-binding protein. Oncogene 25: 1143-52

  23. Yun YP, Joo JD, Lee JY, Nam HY, Kim YH, Lee KH, Lim CS, Kim HJ, Lim YG, Lim Y. 2005. Induction of nuclear factor-kappaB activation through TAK1 and NIK by diesel exhaust particles in L2 cell lines. Toxicol Lett 155: 337-42

  24. Ryu CH, Kim SW, Lee KH, Lee JY, Kim H, Lee WK, Choi BH, Lim Y, Kim YH, Lee KH, Hwang TK, Jun TY, Rha HK. 2005. The merlin tumor suppressor interacts with Ral guanine nucleotide dissociation stimulator and inhibits its activity. Oncogene 24: 5355-64

  25. Jung JR, Kim H, Jeun SS, Lee JY, Koh EJ, Ji C. 2005. The Phosphorylation status of merlin is important for regulating the Ras-ERK pathway. Mol Cells 20: 196-200

  26. Choi JK, Lee SG, Lee JY, Nam HY, Lee WK, Lee KH, Kim HJ, Lim Y. 2005. Silica induces human cyclooxygenase-2gene expression through  the NF-kappaB signaling pathway. J Environ Pathol Toxicol Oncol 24: 163-74

  27. Nam HY, Choi BH, Lee JY, Lee SG, Kim YH, Lee KH, Yoon HK, Song JS, Kim HJ, Lim Y. 2004. The role of nitric oxide in the particulate matter (PM2.5)-induced NFkappaB activation in lung epithelial cells. Toxicol Lett 148: 95-102

  28. Lee JY, Kim H, Ryu CH, Kim JY, Choi BH, Lim Y, Huh PW, Kim YH, Lee KH, Jun TY, Rha HK, Kang JK, Choi CR. 2004. Merlin, a tumors suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity. J Biol Chem 279: 30265-73

  29. Lee IK, Kim KS, Kim H, Lee JY, Ryu CH, Chun HJ, Lee KU, Lim Y, Kim YH, Huh PW, Lee KH, Han SI, Jun TY, RhaHK. 2004. MAP, a protein interacting with a tumor suppressor, merlin, through the run domain. Biochem Biophys Res Commun 325: 774-83

  30.  Kim H*, Kwak NJ*, Lee JY, Choi BH, Lim Y, Ko YJ, Kim YH, Huh PW, Lee KH, Rha HK, Wang YP. 2004. Merlin neutralizes the inhibitory effect of Mdm2 on p53. J Biol Chem 279: 7812-8

  31. Cho H, Lee JY, Kwak NJ, Lee KH, Rha S, Kim YH, Cho YY, Yang KH, Kim K, Lim Y. 2003. Silica induces nuclear factor-kappaB activation through TAK1 and NIK in Rat2 cell line. Toxicol Lett 143: 323-30

 

Publications

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